Calm the System. Restore Balance. Perform with Clarity.
Performance is not only physical. It is mental. Emotional. Neurological. When sleep is inconsistent, focus is fragmented, and stress is elevated—the issue is not effort. It is regulation. Health-Grail 5-HTP is formulated to support the system responsible for that regulation—helping your body produce serotonin, a key neurotransmitter tied to mood, sleep, and overall cognitive balance.
What It Does
5-HTP (5-Hydroxytryptophan) is a direct precursor to serotonin, a neurotransmitter that influences:
- Mood stability and emotional balance
- Sleep quality and recovery cycles
- Appetite regulation and satiety
- Cognitive function and mental clarity
By increasing serotonin production, 5-HTP may help support a more stable internal state—allowing for greater consistency in how you think, feel, and perform. It also plays a role in melatonin production, further supporting sleep quality and recovery.
What’s Inside
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5-Hydroxytryptophan (from Griffonia simplicifolia seed extract) — a naturally derived amino acid compound that is the direct precursor to serotonin; extracted from the seeds of the West African Griffonia simplicifolia plant
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Calcium (as Calcium Carbonate) — supports nerve function and plays a role in neurotransmitter release
The Health-Grail Standard
No fillers. No proprietary blends. No unnecessary additives. Third-party tested for purity, potency, and consistency. This is not a temporary solution. It is a foundational input for mental and recovery performance.
Who It Is For
Individuals seeking to improve sleep quality and nightly recovery, support mood stability and stress response, enhance mental clarity and daily focus, and build a more consistent internal baseline for performance.
How to Use
Take two (2) capsules once daily, 20–30 minutes before a meal with 8 oz of water. Best taken in the evening to support sleep and recovery, or as directed by a healthcare professional.
Amount: 60 capsules | Gross Weight: 0.25 lb (113g) | Made in USA
Frequently Asked Questions
What is 5-HTP and what does it do?
5-HTP (5-Hydroxytryptophan) is a naturally occurring amino acid compound that the body uses to produce serotonin—a neurotransmitter that regulates mood, sleep, appetite, and cognitive function. Unlike serotonin itself, 5-HTP can cross the blood-brain barrier, making it an effective way to support serotonin levels.
What is Griffonia simplicifolia?
Griffonia simplicifolia is a West African plant whose seeds are one of the richest natural sources of 5-HTP. Health-Grail uses a standardized extract from Griffonia simplicifolia seeds to ensure consistent potency and purity in every capsule.
Can 5-HTP help with sleep?
Yes. Serotonin is a precursor to melatonin—the hormone that regulates your sleep-wake cycle. By supporting serotonin production, 5-HTP may help improve sleep onset, sleep quality, and overall recovery cycles. It is best taken in the evening for this purpose.
Does 5-HTP help with anxiety and mood?
5-HTP may help support mood balance and reduce anxiety by increasing serotonin availability in the brain. Serotonin is closely tied to emotional regulation, and low serotonin levels are associated with mood instability and anxiety. Research suggests 5-HTP may have mood-supporting effects with consistent use.
Can 5-HTP help with appetite and weight management?
Yes. Serotonin plays a role in appetite regulation and satiety signaling. Studies suggest 5-HTP may help reduce caloric intake by increasing feelings of fullness, making it a useful tool for individuals managing their weight alongside diet and exercise.
How long does 5-HTP take to work?
Most individuals notice improvements in sleep quality and mood within 1–2 weeks of consistent daily use. Full benefits for mood stabilization and appetite regulation typically develop over 4–6 weeks.
Should I take 5-HTP in the morning or at night?
For sleep support, 5-HTP is best taken in the evening, 30–60 minutes before bed. For mood and appetite support throughout the day, it can be taken with meals. Consult a healthcare professional for personalized guidance.
Can I take 5-HTP with other supplements?
5-HTP can be combined with magnesium (for sleep support) and other wellness supplements. However, it should NOT be combined with antidepressants (SSRIs, MAOIs) or other serotonin-affecting medications without consulting a healthcare professional, as this may cause serotonin syndrome.
Is 5-HTP a natural supplement?
Yes. Health-Grail 5-HTP is derived from the seeds of Griffonia simplicifolia—a natural plant source. It contains no synthetic serotonin or pharmaceutical compounds.
Is this product suitable for vegans?
The active ingredient (5-HTP from Griffonia simplicifolia) is plant-derived. However, this product uses a gelatin capsule, which is animal-derived and not suitable for vegans or vegetarians.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before use. Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.